http://av.kenzym.com/index.php/av/issue/feedAdvanced Virology2024-02-13T00:00:00+00:00Tahir Farooq, PhDtahir.farooq@kenzym.comOpen Journal Systems<p>Advanced Virology is online, open access and peer-reviewed journal that aims to comprehensively cover articles on all aspects of virology, including research on the viruses of animals, plants, insects, archaea, fungi, bacteria and protozoa. Advanced Virology publishes original research articles, review papers, opinions, case studies, and short communications.</p>http://av.kenzym.com/index.php/av/article/view/8Strategies for the control of Cotton leaf curl virus (CLCuV): Unveiling molecular mechanisms, overcoming challenges, and pursuing sustainable solutions2023-12-28T06:09:01+00:00Marium Qureshimariumkhanqureshi2010@gmail.comAli Razammg.aliraza@gmail.comAnam Tanveer anamtanveer@gcuf.edu.pkSara Janiadsara.9005@wum.edu.pkAamir Riazaamirriaz33@gmail.comAnam Sharifanamsharif6@hotmail.comAqib Zebaqibzeb@yahoo.comSumera Sabirsabir_sb@yahoo.comMuhammad Asifmasifashfaq2417@gmail.comMusharaf Hassanmusharafmayo36@gmail.com<p>Cotton leaf curl virus (CLCuV) represents a critical threat to cotton cultivation, significantly impacting the agricultural sector through its influence on host-pathogen dynamics. This review delves into the nature of CLCuV, outlining the molecular mechanisms underlying the virus-host interactions and its broader implications on crop yield and quality. Recent advancements in sustainable disease management are explored, highlighting the integration of genetic engineering techniques such as CRISPR-Cas9 and advancements in remote sensing technologies, which offer promising pathways for developing disease-resistant cotton varieties. The manuscript provides a comprehensive analysis of current strategies and innovations in combating CLCuV, including the role of genetically modified cotton and integrated pest management in enhancing crop resilience. Furthermore, it discusses the potential of molecular biology and genetic engineering to usher in a new era of sustainable agriculture. Looking ahead, this work underscores the importance of continued research and collaboration in developing eco-friendly and efficient disease management strategies. Ultimately, this review contributes to the existing body of knowledge by offering new insights into the molecular basis of CLCuV resistance, paving the way for innovative approaches to safeguard global cotton production.</p>2024-06-25T00:00:00+00:00Copyright (c) 2024 Marium Qureshi, Ali Raza, Anam Tanveer , Sara Janiad, Aamir Riaz, Anam Sharif, Aqib Zeb, Sumera Sabir, Muhammad Asif, Musharaf Hassanhttp://av.kenzym.com/index.php/av/article/view/5Harnessing the bacteriophages to deal with canker infection of kiwi fruit: challenges and future perspective2023-12-04T07:40:12+00:00Ali Razarazaali1019@gmail.comMusharaf Hassanmusharafmayo36@gmail.comSara Janiadsara.9005@wum.edu.pkAamir Riazaamirriaz33@gmail.comAli Khanalikhan.phyto@gmail.comZia Ur Rehmanziaurrehmanrajput7@gmail.comMuhammad Saleemm.saleem@uo.edu.pk<p>The worldwide kiwifruit industry has suffered significant economic losses in recent decades as a result of the destructive bacterial plant disease <em>Pseudomonas syringae </em>pv<em>. actinidiae</em> (Psa). Existing control approaches, which depend on the use of copper bactericides and antibiotics, are facing growing challenges due to the rise of resistance to antibiotics and ecological issues. Although biocontrol techniques show promise in laboratory settings, their efficacy in real-world field situations remains unclear. In order to tackle this issue, the emergence of a phage-based biocontrol method becomes a vital alternative, considering the precise targeting of bacteriophages (phages) towards the particular bacteria and their ecologically benign characteristics. This thorough assessment commences by delineating the repercussions of Psa-induced kiwifruit canker, underscoring the need for pioneering management strategies. The text explores the many types and strengths of Psa strains, and then shifts its attention to recent progress in the identification and description of Psa phages. The main topics discussed are the physical structure of phages, the spectrum of organisms they may infect, their ability to destroy bacterial cells, the study of their genetic material, and the process by which they break down bacterial cells. The review examines biocontrol tactics and their possible obstacles in kiwifruit orchards, specifically focusing on abiotic variables such as elevated temperature, UV irradiation and severe pH. The manuscript highlights the crucial importance of phages in efficiently controlling Psa infections, providing a sustainable and focused approach for safeguarding plants.</p>2024-02-13T00:00:00+00:00Copyright (c) 2024 Ali Raza, Musharaf Hassan, Sara Juniad, Aamir Riaz, Ali Khan, Zia Ur Rehman, Muhammad Saleem